Acute Ischemic Stroke

Unraveling the intricate molecular and cellular mechanisms underlying the progression of Atherosclerosis and CAD remains a challenge. Understanding how these conditions develop and evolve is crucial for developing targeted interventions.

In cases where intravenous thrombolytics are not sufficient or if the clot is large, endovascular therapy may be considered. A catheter is threaded through the blood vessels to the clot site, and a mechanical device is used to physically remove the clot.

Antiplatelet drugs, such as aspirin or clopidogrel, are often prescribed to inhibit platelet aggregation and prevent the formation of new blood clots. Aspirin is commonly administered as a prophylaxis for stroke as well as in the acute phase. Dual antiplatelet therapy may be considered in certain cases.

Maintaining optimal blood pressure is crucial in stroke management. After an acute event, blood pressure may need to be lowered gradually to reduce the risk of bleeding.

Anticoagulant medications may be used in specific cases, especially when atrial fibrillation is present. While vitamin K antagonists like warfarin were used for decades, direct oral anticoagulants are nowadays mainly used to prevent the formation of blood clots.

Supportive measures such as oxygen therapy, fluid management, and maintaining a stable body temperature are essential to support overall patient well-being after acute ischemic stroke.

Rapid identification of stroke symptoms, activation of emergency services, and prompt initiation of appropriate treatment contribute significantly to favorable outcomes of a stroke.